Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 9/20 | 0.40 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602077 | 0.90 | ALDH1A1 (0.39) | ALDH1A1TSHRRORC | |
| SCHEMBL8602830 | 0.83 | TSHR (0.46) | ALDH1A1TSHRDHODHRAB9A | |
| SCHEMBL8600301 | 0.75 | PIK3C2B (0.46) | LCKPIK3C2BDHODHRAB9A | |
| SCHEMBL8670588 | 0.74 | RORC (0.35) | PIK3C2BRORC | |
| SCHEMBL8601990 | 0.73 | KMT2A (0.40) | RAB9APDK1PDK2PDK3PDK4 | |
| Hydrochloric Acid SCHEMBL8599168 | 0.70 | SLC11A2 (0.38) | LCK | |
| SCHEMBL8668207 | 0.68 | IRAK4 (0.45) | PIK3C2BALDH1A1RAB9A | |
| SCHEMBL8602071 | 0.68 | MAPT (0.46) | ALDH1A1 | |
| SCHEMBL8601368 | 0.68 | MAPT (0.46) | PIK3C2BALDH1A1TSHR | |
| SCHEMBL8599739 | 0.67 | KMT2A (0.41) | PIK3C2BALDH1A1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |