SCHEMBL8600359

SCHEMBL8600359

Fc1cc(Cl)c(OC2CCCC2)cc1N=C=S

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPOX P50336 2/20 0.42
SCN9A Q15858 12/20 0.41
CSNK2A1 P68400 2/20 0.40
HPGD P15428 1/20 0.32
KMO O15229 1/20 0.32
FURIN P09958 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8602432 0.94 PPOX (0.36) PPOXSCN9ACSNK2A1
SCHEMBL1531208 0.86 PPOX (0.45) PPOXSCN9ACSNK2A1HPGDKMO
SCHEMBL9770920 0.82
SCHEMBL8599002 0.81 SCN9A (0.34) PPOXSCN9AHPGD
SCHEMBL8598609 0.79 PPOX (0.42) PPOXSCN9AHPGD
SCHEMBL8601518 0.77 PPOX (0.45) PPOXSCN9AHPGD
SCHEMBL8601522 0.77 SCN9A (0.36) PPOXSCN9A
SCHEMBL9770905 0.76 NAAA (0.39) SCN9AHPGD
SCHEMBL7535311 0.76 NPC1 (0.38) PPOXHPGD
SCHEMBL8600411 0.76 RORC (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0626370-B1 Process for producing aromatic isothiocyanate derivatives SUMITOMO CHEMICAL CO (JP) 1998-02-11 EP disclosed
EP-0626370-A1 Process for producing aromatic isothiocyanate derivatives SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1994-11-30 EP disclosed