Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PPOX | P50336 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600411 | 0.95 | RORC (0.32) | GAA | |
| SCHEMBL8598609 | 0.83 | PPOX (0.42) | SCN9ANPC1RAB9ASMN1; SMN2PPOX | |
| SCHEMBL9770905 | 0.82 | NAAA (0.39) | SCN9ANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8601522 | 0.81 | SCN9A (0.36) | SCN9ANPC1RAB9APPOX | |
| SCHEMBL8601518 | 0.81 | PPOX (0.45) | SCN9ANPC1RAB9ASMN1; SMN2PPOX | |
| SCHEMBL8600359 | 0.81 | PPOX (0.42) | SCN9APPOXHPGD | |
| SCHEMBL8603030 | 0.80 | CUL4A (0.40) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| SCHEMBL8601482 | 0.78 | PPOX (0.41) | NPC1RAB9ASMN1; SMN2PPOXHPGD | |
| SCHEMBL8603023 | 0.78 | NPC1 (0.33) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| SCHEMBL8602564 | 0.78 | NPC1 (0.38) | SCN9ANPC1RAB9ASMN1; SMN2PPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |