Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410259 | 0.89 | SMN1; SMN2 (0.39) | NPC1RAB9ASMN1; SMN2GAASLC6A3 | |
| SCHEMBL8599002 | 0.82 | SCN9A (0.34) | NPC1RAB9ASMN1; SMN2GAASLC6A3 | |
| SCHEMBL8603023 | 0.81 | NPC1 (0.33) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| SCHEMBL9051631 | 0.80 | GAA (0.40) | NPC1RAB9ASMN1; SMN2GAAHPGD | |
| SCHEMBL8598609 | 0.79 | PPOX (0.42) | NPC1RAB9ASMN1; SMN2GAAHPGD | |
| SCHEMBL8602421 | 0.78 | ALDH1A1 (0.37) | SMN1; SMN2GAAHPGDPOLBMAPT | |
| SCHEMBL8601522 | 0.78 | SCN9A (0.36) | NPC1RAB9AMAPTSCN9ALMNA | |
| SCHEMBL8601518 | 0.78 | PPOX (0.45) | NPC1RAB9ASMN1; SMN2GAAHPGD | |
| SCHEMBL10471483 | 0.77 | LMNA (0.40) | NPC1RAB9ASMN1; SMN2GAASLC6A3 | |
| SCHEMBL8601499 | 0.77 | PTGS1 (0.32) | NPC1RAB9ASMN1; SMN2HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039331-A | Condensed heterocyclic derivatives and herbicides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-13 | — | — | US | disclosed |
| EP-0304920-A2 | Condensed heterocyclic derivatives, process for their production and herbicides | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-03-01 | — | — | EP | disclosed |