Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084300 | 0.75 | HTR3E (0.45) | MAPTRXFP1RHEBMCL1 | |
| SCHEMBL8599075 | 0.74 | MAOA (0.39) | MAOAMAOBMEN1KMT2ANPSR1 | |
| SCHEMBL15010455 | 0.72 | ROCK2 (0.52) | MAOAMAOBSCN9ADAOCYP3A4 | |
| SCHEMBL8602858 | 0.71 | IMPDH2 (0.56) | MAOAMAOBMAPTPPARGSMN1; SMN2 | |
| SCHEMBL16296715 | 0.71 | MAOA (0.47) | MAOAMAOBSCN9ADAOSLC6A4 | |
| SCHEMBL8602871 | 0.70 | NPC1 (0.53) | MEN1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL8600852 | 0.70 | RHEB (0.36) | SMN1; SMN2RHEB | |
| SCHEMBL8603229 | 0.70 | RAB9A (0.56) | MEN1MAPTKMT2ANPSR1PPARG | |
| SCHEMBL19692864 | 0.70 | QPCT (0.43) | MAOAMAOBSCN9ADAOCDC7 | |
| SCHEMBL29650198 | 0.70 | QPCT (0.43) | MAOAMAOBSCN9ADAOCDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |