SCHEMBL8602500

SCHEMBL8602500

Cc1cccc(-c2c(N)c(N)cc3ccccc23)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.44
HEXA P06865 1/20 0.42
HEXB P07686 1/20 0.42
KMT2A Q03164 2/20 0.41
ADORA1 P30542 2/20 0.39
ENPP1 P22413 1/20 0.39
NR1I3 Q14994 2/20 0.38
NPC1 O15118 1/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2A6 P11509 1/20 0.38
DPP4 P27487 1/20 0.38
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 1/20 0.37
TSHR P16473 2/20 0.37
CYP3A4 P08684 1/20 0.37
HPGD P15428 1/20 0.37
KEAP1 Q14145 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CNR1 P21554 2/20 0.37
CNR2 P34972 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27930163 0.83 ALOX5 (0.52) RAB9AHEXAHEXBKMT2AENPP1
SCHEMBL28174443 0.83 ACHE (0.43) RAB9AKMT2AALDH1A1MEN1TSHR
SCHEMBL12124161 0.78 ALDH1A1 (0.46) RAB9AKMT2ANPC1CYP1A2CYP2A6
SCHEMBL25656537 0.78 RAB9A (0.46) RAB9AHEXAHEXBKMT2AADORA1
SCHEMBL488939 0.74 ACHE (0.50) RAB9AHEXAHEXBKMT2AENPP1
SCHEMBL26619981 0.74 HPRT1 (0.51) RAB9AHEXAHEXBKMT2AADORA1
SCHEMBL7909976 0.73 CYP2A6 (0.46) RAB9AHEXAHEXBKMT2AENPP1
SCHEMBL3869774 0.73 RAB9A (0.52) RAB9AHEXAHEXBKMT2AADORA1
SCHEMBL6930975 0.73 RAB9A (0.52) RAB9AHEXAHEXBKMT2AADORA1
SCHEMBL584973 0.73 ALDH1A1 (0.47) KMT2AALDH1A1MEN1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5767315-A CHARGE TRANSFER COMPOUNDS MITA INDUSTRIAL CO., LTD. (JP) 1998-06-16 US disclosed