Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 10/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 10/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603532 | 0.85 | ADAMTS4 (0.44) | MMP9TDP1MMP2ADAMTS4POLB | |
| Chloromethane SCHEMBL7649372 | 0.80 | MMP2 (0.75) | ALDH1A1MAPTMMP9TDP1MMP2 | |
| SCHEMBL1203540 | 0.80 | MMP2 (0.79) | ALDH1A1MAPTMMP9TDP1MMP2 | |
| SCHEMBL697476 | 0.80 | MMP2 (0.79) | ALDH1A1MAPTMMP9TDP1MMP2 | |
| SCHEMBL697477 | 0.80 | MMP2 (0.79) | ALDH1A1MAPTMMP9TDP1MMP2 | |
| SCHEMBL8603280 | 0.79 | CTSL (0.46) | ALDH1A1MAPTMMP9TDP1MMP2 | |
| Hydrochloric Acid SCHEMBL11133046 | 0.79 | MMP2 (0.77) | ALDH1A1MAPTMMP9TDP1MMP2 | |
| Hydrochloric Acid SCHEMBL3839410 | 0.79 | MMP2 (0.77) | ALDH1A1MAPTMMP9TDP1MMP2 | |
| Hydrochloric Acid SCHEMBL28872216 | 0.78 | MMP2 (0.75) | ALDH1A1MAPTMMP9TDP1MMP2 | |
| SCHEMBL3856155 | 0.77 | MMP2 (0.73) | ALDH1A1MAPTMMP9TDP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710652-B1 | Process for preparing optically active piperazine derivatives and intermediates for preparation | YAMAKAWA CHEMICAL IND (JP) | 1998-03-04 | — | — | EP | disclosed |
| EP-0710652-A2 | Process for preparing optically active piperazine derivatives and intermediates for preparation | YAMAKAWA CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |