Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408810 | 0.88 | CTSK (0.45) | CTSKCTSSCTSLCTSB | |
| SCHEMBL8604140 | 0.83 | CTSK (0.46) | CTSKCTSSCTSLPOLBGAA | |
| SCHEMBL8097897 | 0.82 | CTSS (0.41) | CTSKCTSSCTSLPOLBSYK | |
| SCHEMBL9326544 | 0.81 | CTSK (0.42) | CTSKCTSSCTSLPOLBGAA | |
| SCHEMBL7405615 | 0.81 | RAB9A (0.42) | CTSKPOLBGAASYKMAPT | |
| SCHEMBL7405620 | 0.81 | RAB9A (0.42) | CTSKPOLBGAASYKMAPT | |
| SCHEMBL9329333 | 0.80 | CTSB (0.43) | CTSKCTSSCTSLPOLBGAA | |
| SCHEMBL9326476 | 0.79 | MAPT (0.43) | CTSKPOLBGAASYKCTSB | |
| SCHEMBL9326520 | 0.78 | CTSK (0.39) | CTSKCTSSCTSLPOLBGAA | |
| SCHEMBL9326565 | 0.78 | CTSK (0.39) | CTSKCTSSCTSLPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530161-A | TREATING RHEUMATOID ARTHRITIS, PROMOTING WOUND HEALING | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1996-06-25 | — | — | US | disclosed |
| US-5310763-A | Wound healing, rheumatoid arthritis | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-10 | — | — | US | disclosed |
| EP-0446267-B1 | HYDROXAMIC ACID BASED COLLAGENASE INHIBITORS | BRITISH BIO TECHNOLOGY (GB) | 1994-04-13 | — | — | EP | disclosed |
| EP-0445206-B1 | HYDROXAMIC ACID BASED COLLAGENASE INHIBITORS | BRITISH BIO TECHNOLOGY (GB) | 1994-03-16 | — | — | EP | disclosed |
| US-5240958-A | HYDROXAMIC ACID BASED COLLAGENASE INHIBITORS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-31 | — | — | US | disclosed |