Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | S100B | P04271 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 4/20 | 0.37 |
| ▸ | CASP1 | P29466 | 3/20 | 0.37 |
| ▸ | CASP7 | P55210 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604154 | 0.81 | KDM4E (0.41) | ARALDH1A1CYP3A4TDP1MAPK1 | |
| SCHEMBL8601909 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL11616880 | 0.76 | TERT (0.52) | ARALDH1A1L3MBTL1CYP3A4TDP1 | |
| SCHEMBL9014074 | 0.73 | S100B (0.47) | ARALDH1A1L3MBTL1CYP3A4TDP1 | |
| SCHEMBL3836298 | 0.73 | AHR (0.50) | TERTS100BALOX15GAAPDE3B | |
| SCHEMBL8602948 | 0.72 | RXFP1 (0.52) | ALDH1A1L3MBTL1PSMD14MAPTHPGD | |
| SCHEMBL8603563 | 0.71 | PARP1 (0.39) | ALDH1A1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL8601916 | 0.71 | ALDH1A1 (0.53) | ALDH1A1TDP1MAPK1TSHRMAPT | |
| SCHEMBL28408746 | 0.70 | AR (0.71) | AR | |
| SCHEMBL8084300 | 0.69 | HTR3E (0.45) | ALDH1A1TSHRPSMD14MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |