Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3992020 | 0.89 | ALDH1A1 (0.41) | CYP1A2CYP3A4CYP2C9AKR1C3ALDH1A1 | |
| SCHEMBL8605251 | 0.88 | MAPT (0.48) | HDAC6MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11859212 | 0.75 | HPGD (0.56) | HDAC6MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3231863 | 0.73 | PTGS2 (0.44) | MEN1KMT2AAKR1C3ALDH1A1GAA | |
| SCHEMBL9724259 | 0.72 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL7473702 | 0.70 | PTGS2 (0.56) | MEN1KMT2ACYP1A2TSHRAKR1C3 | |
| SCHEMBL3997292 | 0.70 | ALDH1A1 (0.43) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8053596 | 0.69 | GAA (0.44) | HDAC6MEN1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL8606841 | 0.69 | HDAC8 (0.51) | HDAC6KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL11867579 | 0.69 | MEN1 (0.56) | HDAC6MEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721347-A | Esters and amides of substituted pyrrole acetic acids | CELL PATHWAYS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0485157-A2 | Esters and amides of substituted pyrrole acetic acids | FGN, INC. (US) | 1992-05-13 | — | — | EP | disclosed |