SCHEMBL8609786

SCHEMBL8609786

C=Cc1ccccc1C1CCc2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 1/20 0.44
IDO1 P14902 2/20 0.41
PDPK1 O15530 1/20 0.41
HTR1A P08908 4/20 0.40
SIGMAR1 Q99720 2/20 0.40
ALDH1A1 P00352 1/20 0.39
CYP11B2 P19099 1/20 0.39
CHRNA7 P36544 1/20 0.38
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1321366 0.78 ADRA1A (0.41) ADRA1AIDO1PDPK1SIGMAR1CYP11B2
SCHEMBL27632012 0.76 HTR2A (0.50) ADRA1AIDO1PDPK1SIGMAR1CYP11B2
SCHEMBL9570548 0.75 ADRA1A (0.44) ADRA1AIDO1PDPK1HTR1ASIGMAR1
SCHEMBL28958240 0.72 ALDH1A1 (0.43) ADRA1AIDO1PDPK1HTR1AALDH1A1
SCHEMBL2984209 0.72 IDO1 (0.48) ADRA1AIDO1PDPK1SIGMAR1CYP11B2
SCHEMBL133896 0.72 HTR2A (0.49) ADRA1AIDO1PDPK1SIGMAR1CYP11B2
SCHEMBL8849605 0.72 DDB1 (0.53) ADRA1AIDO1PDPK1SIGMAR1CYP11B2
SCHEMBL5710152 0.72 PIN1 (0.51) ADRA1AIDO1PDPK1SIGMAR1CYP11B2
SCHEMBL15846513 0.71 PIN1 (0.47) ADRA1AIDO1PDPK1SIGMAR1CYP11B2
SCHEMBL503849 0.71 SIGMAR1 (0.62) ADRA1ASIGMAR1CYP11B2MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0150908-B1 Use of Curable impregnant compositions for impregnating electrical appliances NIPPON PETROCHEMICALS CO LTD (JP) 1998-04-15 EP disclosed
US-4670348-A Electrical appliance impregnated with a curable impregnant composition NIPPON PETROCHEMICALS CO., LTD. (JP) 1987-06-02 US disclosed
EP-0150908-A1 Use of Curable impregnant compositions for impregnating electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-08-07 EP disclosed