Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.65 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12371901 | 0.87 | HDAC8 (0.83) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL10474875 | 0.83 | ENPP2 (0.62) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL27600908 | 0.83 | ENPP2 (0.62) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL7834329 | 0.83 | ENPP2 (0.62) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL7835190 | 0.83 | ENPP2 (0.62) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL8585476 | 0.81 | HDAC4 (0.70) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL7129534 | 0.81 | HDAC3 (0.73) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL7835578 | 0.81 | CA1 (0.63) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL8089351 | 0.79 | ALDH1A1 (0.62) | L3MBTL1ALDH1A1TP53SMN1; SMN2KDM4E | |
| SCHEMBL8585381 | 0.79 | SIRT1 (0.55) | HDAC8HDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998031689-A1 | NOVEL MIXED BENZENE ACID DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 1998-07-23 | — | — | WO | disclosed |