Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP11A1 | P05108 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614549 | 0.85 | AKR1B1 (0.34) | TYMS | |
| SCHEMBL7639950 | 0.85 | ADRA2A (0.37) | CA9TYMS | |
| SCHEMBL8611882 | 0.82 | ALDH1A1 (0.39) | CYP3A4PDE4DCA9 | |
| SCHEMBL8610413 | 0.82 | NPSR1 (0.43) | NPSR1 | |
| SCHEMBL8614404 | 0.81 | CYP19A1 (0.35) | CYP19A1CA9TYMS | |
| SCHEMBL8610304 | 0.74 | ADRA2A (0.40) | CYP19A1 | |
| SCHEMBL9431991 | 0.72 | NPSR1 (0.40) | CYP19A1NPSR1 | |
| SCHEMBL8613975 | 0.70 | KDM4E (0.30) | CA9 | |
| SCHEMBL9140465 | 0.66 | CA9 (0.40) | CYP19A1CYP3A4NPSR1CA9TYMS | |
| SCHEMBL8610348 | 0.66 | AKR1B1 (0.36) | CA9TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618906-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | JUVANTIA PHARMA LTD OY (FI) | 1998-04-22 | — | — | EP | disclosed |
| US-5498623-A | MULTISTAGE REACTION FOR HALOGENATION OF COMPOUNDS, NITRATION, REDUCTION AND CONVERSION TO DIAZONIUM SALT THEN HALOGENATION FOR COGNITIVE DISORDERS | ORION-YHTYMA OY (FI) | 1996-03-12 | — | — | US | disclosed |
| EP-0618906-A1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | ANTII SAKARI HAAPALINNA (FI) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013074-A1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Orion-Yhtymä Oy (FI) | 1993-07-08 | — | — | WO | disclosed |