Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566269 | 0.79 | DRD2 (0.63) | DRD2SIGMAR1ADRA1ACNR2 | |
| SCHEMBL6216977 | 0.76 | DRD2 (0.53) | DRD2SIGMAR1ADRA1ACNR2 | |
| SCHEMBL7966084 | 0.74 | ADRA1D (0.66) | DRD2SIGMAR1ADRA1A | |
| SCHEMBL6968819 | 0.73 | OPRM1 (0.41) | SIGMAR1 | |
| SCHEMBL7677837 | 0.72 | DRD2 (0.59) | DRD2SIGMAR1ADRA1ACNR2 | |
| SCHEMBL6197779 | 0.71 | DRD2 (0.55) | DRD2SIGMAR1ADRA1A | |
| SCHEMBL7524346 | 0.71 | ADRA1A (0.57) | DRD2SIGMAR1ADRA1A | |
| SCHEMBL6198575 | 0.71 | DRD2 (0.55) | DRD2SIGMAR1ADRA1A | |
| SCHEMBL12501782 | 0.70 | DRD2 (0.65) | DRD2SIGMAR1 | |
| Biphenyl SCHEMBL28784863 | 0.70 | DRD2 (0.62) | DRD2SIGMAR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998051311-A2 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1998-11-19 | — | — | WO | disclosed |