Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.40 |
| ▸ | BIRC2 | Q13490 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | FCER2 | P06734 | 1/20 | 0.32 |
| ▸ | BMP1 | P13497 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6376109 | 0.78 | L3MBTL1 (0.33) | ECE1 | |
| SCHEMBL27813271 | 0.71 | ECE1 (0.47) | ECE1BIRC2HDAC2FOLH1HDAC3 | |
| SCHEMBL4401595 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL21304164 | 0.70 | — | — | |
| SCHEMBL228308 | 0.70 | — | — | |
| SCHEMBL3396230 | 0.69 | — | — | |
| SCHEMBL6412290 | 0.69 | ECE1 (0.41) | ECE1HDAC2FOLH1HDAC3HDAC1 | |
| SCHEMBL27416714 | 0.69 | — | — | |
| SCHEMBL22834424 | 0.68 | BIRC2 (0.41) | BIRC2HDAC2FOLH1HDAC3HDAC1 | |
| SCHEMBL4399338 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835240-A1 | MATRIX METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997002239-A1 | MATRIX METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-01-23 | — | — | WO | disclosed |