Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 5/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | REN | P00797 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HTRA1 | Q92743 | 3/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.44 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.44 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.44 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.44 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613804 | 0.94 | CTSS (0.50) | CTSDCTSBCTSKRENKMT2A | |
| SCHEMBL8620934 | 0.94 | CTSD (0.55) | CTSDCTSBCTSKBACE1REN | |
| SCHEMBL8614984 | 0.89 | CTSD (0.49) | CTSDCTSBCTSKBACE1REN | |
| SCHEMBL8617778 | 0.88 | CTSS (0.56) | CTSDCTSBCTSKRENKMT2A | |
| SCHEMBL8620133 | 0.85 | CTSS (0.55) | CTSDCTSBCTSKRENKMT2A | |
| Hydrochloric Acid SCHEMBL8616110 | 0.84 | CTSB (0.45) | CTSDCTSBCTSK | |
| SCHEMBL8613599 | 0.81 | CTSD (0.56) | CTSDCTSBCTSKRENKMT2A | |
| SCHEMBL8613619 | 0.79 | CTSD (0.53) | CTSDCTSBCTSKRENKMT2A | |
| SCHEMBL8613316 | 0.78 | PSMB8 (0.52) | CTSDCTSBCTSKRENCTSS | |
| SCHEMBL8616203 | 0.78 | CTSS (0.47) | CTSDCTSBCTSKRENKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |