SCHEMBL8615415

SCHEMBL8615415

CCCC[C@H](NCCc1ccccc1)C(N)=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSK P43235 4/20 0.53
TLR2 O60603 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
HPGD P15428 1/20 0.47
CNR2 P34972 1/20 0.47
SIGMAR1 Q99720 2/20 0.46
GGT1 P19440 1/20 0.46
HDAC3 O15379 1/20 0.46
SIRT2 Q8IXJ6 1/20 0.45
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
OPRK1 P41145 1/20 0.43
CAPN1 P07384 1/20 0.43
CTSB P07858 1/20 0.43
MMP3 P08254 1/20 0.43
MMP9 P14780 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8615288 0.99 CTSK (0.52) CTSKTLR2CYP1A2CYP2C9CYP2C19
SCHEMBL30882505 0.86 OPRK1 (0.49) CYP1A2CYP2C9CYP2C19CNR2SIGMAR1
SCHEMBL30882671 0.86 OPRK1 (0.49) CYP1A2CYP2C9CYP2C19CNR2SIGMAR1
SCHEMBL7272134 0.85 TLR2 (0.58) CTSKTLR2CNR2
Hydrochloric Acid SCHEMBL30882685 0.85 OPRK1 (0.48) CYP1A2CYP2C9CYP2C19CNR2SIGMAR1
SCHEMBL2246535 0.82 KEAP1 (0.49) GGT1HDAC3
SCHEMBL29152262 0.82 MMP3 (0.51) CYP2C9CYP2C19GGT1KMT2AMMP3
SCHEMBL7313618 0.82 CA1 (0.47) GGT1OPRK1
SCHEMBL7466897 0.80 CYP3A4 (0.45) CYP1A2CYP2C9CYP2C19SIGMAR1GGT1
SCHEMBL7466905 0.80 CYP3A4 (0.45) CYP1A2CYP2C9CYP2C19SIGMAR1GGT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0838471-A1 PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST SAGAMI CHEMICAL RESEARCH CENTER (JP) 1998-04-29 EP disclosed