Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615656 | 1.00 | L3MBTL1 (0.44) | L3MBTL1SIGMAR1SOAT1MAPK1TDP1 | |
| SCHEMBL8871109 | 1.00 | L3MBTL1 (0.44) | L3MBTL1SIGMAR1SOAT1MAPK1TDP1 | |
| SCHEMBL8871117 | 0.82 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL4182608 | 0.80 | HSD11B1 (0.39) | L3MBTL1SIGMAR1SOAT1ALDH1A1MAPT | |
| SCHEMBL9368035 | 0.79 | L3MBTL1 (0.40) | L3MBTL1MAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL19433531 | 0.78 | SMN1; SMN2 (0.45) | L3MBTL1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL8759052 | 0.77 | HSD11B1 (0.39) | L3MBTL1SIGMAR1SOAT1ALDH1A1MAPT | |
| SCHEMBL4170321 | 0.76 | MMP1 (0.39) | L3MBTL1MAPK1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL8616156 | 0.76 | SIGMAR1 (0.51) | SIGMAR1SOAT1MAPK1TDP1SMN1; SMN2 | |
| SCHEMBL8620049 | 0.76 | HSD11B1 (0.40) | L3MBTL1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716948-A | 3-substituted carbacephems | PFIZER INC. (US) | 1998-02-10 | — | — | US | disclosed |