Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322436 | 0.82 | HRH3 (0.40) | ITGB3ITGA2BHRH3CYP19A1GFER | |
| SCHEMBL8618280 | 0.80 | ITGB3 (0.34) | ITGB3ITGA2BHRH3FAAHCYP19A1 | |
| SCHEMBL8899327 | 0.80 | HRH3 (0.38) | HRH3FAAHCYP19A1GFERMEN1 | |
| SCHEMBL8621090 | 0.80 | MTNR1A (0.36) | ITGB3ITGA2BCYP19A1CHRM3 | |
| SCHEMBL8621103 | 0.74 | ACE (0.34) | ITGB3ITGA2BCYP19A1ITGAVCHRM3 | |
| SCHEMBL8619292 | 0.74 | GPBAR1 (0.34) | — | |
| SCHEMBL8617240 | 0.73 | ITGB3 (0.39) | ITGB3ITGA2BMEN1KMT2AITGAV | |
| SCHEMBL8619325 | 0.73 | MC4R (0.38) | ITGB3ITGA2BCYP19A1MEN1KMT2A | |
| SCHEMBL8619314 | 0.71 | MTNR1A (0.40) | ITGB3ITGA2BCYP19A1MEN1KMT2A | |
| SCHEMBL8618351 | 0.71 | CYP19A1 (0.48) | CYP19A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852045-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-22 | — | — | US | disclosed |