Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322436 | 0.86 | HRH3 (0.40) | HRH3CYP19A1MEN1KMT2AGFER | |
| SCHEMBL8619355 | 0.80 | ITGB3 (0.39) | HRH3CYP19A1FAAHMEN1KMT2A | |
| SCHEMBL8618351 | 0.80 | CYP19A1 (0.48) | CYP19A1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8618280 | 0.77 | ITGB3 (0.34) | HRH3CYP19A1FAAHMEN1KMT2A | |
| SCHEMBL8621090 | 0.75 | MTNR1A (0.36) | CYP19A1ALDH1A1CHRM3 | |
| SCHEMBL8621103 | 0.72 | ACE (0.34) | CYP19A1ALDH1A1LMNACHRM3 | |
| SCHEMBL8619292 | 0.72 | GPBAR1 (0.34) | ALDH1A1KDM4E | |
| SCHEMBL7405338 | 0.72 | ACE (0.56) | HRH3CYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL7320593 | 0.72 | ACE (0.56) | HRH3CYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL8619314 | 0.72 | MTNR1A (0.40) | CYP19A1MEN1KMT2AALDH1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686607-A | Pyridyl ethylation of lactam derivatives | MERCK & CO., INC. (US) | 1997-11-11 | — | — | US | disclosed |