Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617490 | 0.90 | HRH3 (0.49) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL8590131 | 0.87 | MCHR1 (0.53) | SMN1; SMN2MCHR1ALDH1A1KDM4EHRH3 | |
| SCHEMBL8589432 | 0.85 | ALDH1A1 (0.51) | MAPTMEN1KMT2APOLBTP53 | |
| SCHEMBL8619358 | 0.84 | MAPT (0.47) | MAPTMEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL8612301 | 0.81 | THRB (0.52) | TP53LMNAALDH1A1KDM4EHRH3 | |
| SCHEMBL8589629 | 0.80 | HRH3 (0.50) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL8589733 | 0.80 | HRH3 (0.70) | MAPTMCHR1HRH3NPC1RAB9A | |
| SCHEMBL8587504 | 0.80 | HRH3 (0.53) | MCHR1CA12CA1CA2CA9 | |
| SCHEMBL8589516 | 0.79 | MEN1 (0.53) | MAPTMEN1KMT2AMAPK1CYP1A2 | |
| SCHEMBL8587717 | 0.79 | RAB9A (0.53) | MAPTMEN1KMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |