Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL925819 | 0.81 | GABRA1 (0.33) | SNCA | |
| SCHEMBL855886 | 0.78 | PKM (0.41) | HTR2A | |
| SCHEMBL925505 | 0.73 | HPGD (0.35) | — | |
| SCHEMBL28879829 | 0.72 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL318499 | 0.69 | KDM4E (0.44) | — | |
| SCHEMBL29953131 | 0.69 | KDM4E (0.44) | — | |
| SCHEMBL31378001 | 0.69 | SLC6A4 (0.36) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL980220 | 0.69 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL1937100 | 0.69 | ALDH1A1 (0.33) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5398528 | 0.66 | LOXL2 (0.43) | SLC6A4SLC6A2SLC6A3HTR2ALOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9055749-B2 | Insecticidal arylpyrrolines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-16 | — | — | US | disclosed |
| EP-2432762-B1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2015-02-25 | — | — | EP | disclosed |
| US-20140024680-A1 | Insecticidal Arylpyrrolines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-23 | — | — | US | disclosed |
| US-8410141-B2 | Insecticidal arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2013-04-02 | — | — | US | disclosed |
| US-8304371-B2 | Insecticidal arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20120108635-A1 | Insecticidal Arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2012-05-03 | — | — | US | disclosed |
| EP-2432762-A1 | INSECTICIDAL ARYLPYRROLINES | Bayer CropScience AG (DE) | 2012-03-28 | — | — | EP | disclosed |
| US-20110003690-A1 | INSECTICIDAL ARYLPYRROLINES | BAY CROPSCIENCE AG (DE) | 2011-01-06 | — | — | US | disclosed |
| WO-2010133336-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | WO | disclosed |
| EP-2242739-A1 | INSECTICIDAL ARYLPYRROLINES | Bayer CropScience AG (DE) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009097992-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003690-A1 | INSECTICIDAL ARYLPYRROLINES | DDT, ACHE, CYP1A2 | SLC6A4 4792/4885SLC6A2 3511/4885SLC6A3 3986/4885 |
| US-20140024680-A1 | Insecticidal Arylpyrrolines | DDT, ACHE, CYP1A2 | SLC6A4 4821/4885SLC6A2 3859/4885SLC6A3 4258/4885 |
| US-20120108635-A1 | Insecticidal Arylpyrrolines | DDT, ACHE, CYP1A2 | SLC6A4 4821/4885SLC6A2 3859/4885SLC6A3 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.