Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.35 |
| ▸ | HTR3B | O95264 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326437 | 0.79 | KDM4E (0.43) | KDM4EMAPTMAPK1GAAL3MBTL1 | |
| SCHEMBL8326614 | 0.70 | ALDH1A1 (0.42) | KDM4EMAPK1GAAL3MBTL1ACHE | |
| SCHEMBL8328374 | 0.66 | ACHE (0.42) | ACHE | |
| SCHEMBL8117468 | 0.66 | MAPT (0.67) | KDM4EMAPTMAPK1 | |
| SCHEMBL1507008 | 0.65 | LMNA (0.67) | KDM4EMAPT | |
| SCHEMBL16226139 | 0.65 | POLB (0.61) | KDM4EMAPTMAPK1 | |
| SCHEMBL13869588 | 0.65 | ALDH1A1 (0.69) | KDM4EMAPTMAPK1 | |
| SCHEMBL8327173 | 0.65 | PRKAA2 (0.42) | ACHEDRD3BACE1 | |
| SCHEMBL11939427 | 0.63 | MAPK1 (0.58) | KDM4EMAPTMAPK1GAA | |
| SCHEMBL4419829 | 0.62 | MAPT (0.54) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |