Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622258 | 0.86 | MAOB (0.47) | MAOBMAOARAB9AKMT2A | |
| SCHEMBL1539419 | 0.84 | ACHE (0.40) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL1539409 | 0.84 | LMNA (0.50) | SMN1; SMN2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1539415 | 0.81 | THRA (0.42) | MAOBL3MBTL1MEN1RAB9AKMT2A | |
| SCHEMBL8623315 | 0.79 | POLB (0.47) | SMN1; SMN2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1539440 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL14018700 | 0.79 | MAOB (0.54) | SMN1; SMN2MAOBTDP1RAB9A | |
| SCHEMBL8590315 | 0.78 | GRM5 (0.41) | GRM5SMN1; SMN2F2MAOB | |
| SCHEMBL8624161 | 0.77 | MAPT (0.49) | SMN1; SMN2MAOBL3MBTL1MAOAMEN1 | |
| SCHEMBL2561446 | 0.76 | LIPG (0.41) | GRM5SMN1; SMN2F2MAOBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |