Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TACR3 | P29371 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620632 | 0.88 | HPGD (0.44) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8620380 | 0.87 | CA2 (0.39) | KDM4EALDH1A1SMN1; SMN2TACR3MEN1 | |
| SCHEMBL8619826 | 0.86 | ALDH1A1 (0.44) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8616302 | 0.84 | PDE10A (0.43) | KDM4EALDH1A1SMN1; SMN2TACR3MEN1 | |
| SCHEMBL8617947 | 0.84 | MEN1 (0.43) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8616497 | 0.83 | TACR3 (0.61) | KDM4EALDH1A1SMN1; SMN2TACR3MEN1 | |
| SCHEMBL8620945 | 0.82 | NQO2 (0.56) | KDM4EALDH1A1SMN1; SMN2TACR3MEN1 | |
| SCHEMBL8620866 | 0.82 | ALDH1A1 (0.46) | KDM4EALDH1A1SMN1; SMN2TACR3MEN1 | |
| SCHEMBL8614352 | 0.82 | PDE10A (0.43) | KDM4EALDH1A1SMN1; SMN2TACR3MEN1 | |
| SCHEMBL8614038 | 0.82 | PDE10A (0.39) | KDM4EALDH1A1SMN1; SMN2TACR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |