Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.44 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613084 | 0.81 | GRIN2B (0.54) | GRIN2BHRH3ALDH1A1GAAL3MBTL1 | |
| SCHEMBL8618958 | 0.81 | HRH3 (0.51) | GRIN2BHRH3TRPV6CHKAHIF1A | |
| SCHEMBL8620385 | 0.78 | GRIN2B (0.50) | GRIN2BHRH3TRPV6ALDH1A1L3MBTL1 | |
| SCHEMBL3640868 | 0.76 | CHKA (0.50) | GRIN2BHRH3CHKAALDH1A1L3MBTL1 | |
| SCHEMBL8790772 | 0.76 | CHKA (0.50) | GRIN2BHRH3CHKAALDH1A1L3MBTL1 | |
| SCHEMBL18867080 | 0.75 | L3MBTL3 (0.53) | GRIN2BHRH3CHKAALDH1A1L3MBTL1 | |
| SCHEMBL3716319 | 0.75 | L3MBTL1 (0.67) | GRIN2BHRH3ALDH1A1GAAKDM4E | |
| Hydrochloric Acid SCHEMBL3716101 | 0.74 | L3MBTL1 (0.65) | GRIN2BHRH3ALDH1A1GAAKDM4E | |
| SCHEMBL8613090 | 0.73 | DRD2 (0.49) | GRIN2BHRH3TRPV6ALDH1A1HIF1A | |
| SCHEMBL8613757 | 0.72 | HRH3 (0.61) | HRH3TRPV6HIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786371-A | INHIBIT AGGREGATION OF BLOOD PLATELETS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-07-28 | — | — | US | disclosed |