Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620387 | 0.81 | MAPT (0.48) | GRIN2BMAPTF10DRD3DRD2 | |
| SCHEMBL8613084 | 0.81 | GRIN2B (0.54) | GRIN2BMAPTDRD3DRD2HRH3 | |
| SCHEMBL8618953 | 0.78 | GRIN2B (0.48) | GRIN2BDRD3DRD2HRH3ALDH1A1 | |
| SCHEMBL3716319 | 0.77 | L3MBTL1 (0.67) | GRIN2BMAPTDRD3DRD2HRH3 | |
| Hydrochloric Acid SCHEMBL3710266 | 0.76 | MAPT (0.60) | MAPTDRD3DRD2ALDH1A1TRPV6 | |
| Hydrochloric Acid SCHEMBL3716101 | 0.76 | L3MBTL1 (0.65) | GRIN2BMAPTDRD3DRD2HRH3 | |
| SCHEMBL3784411 | 0.74 | TRPV6 (0.64) | MAPTALDH1A1TRPV6MBTD1L3MBTL3 | |
| SCHEMBL8613090 | 0.74 | DRD2 (0.49) | GRIN2BDRD3DRD2HRH3ALDH1A1 | |
| SCHEMBL7961303 | 0.74 | F10 (0.54) | F10HRH3HRH1HRH2 | |
| Hydrochloric Acid SCHEMBL3708908 | 0.74 | MAPT (0.81) | MAPTDRD2HTR1AMBTD1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786371-A | INHIBIT AGGREGATION OF BLOOD PLATELETS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-07-28 | — | — | US | disclosed |