Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 19/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899327 | 0.80 | HRH3 (0.38) | CYP19A1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL7322436 | 0.76 | HRH3 (0.40) | CYP19A1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL8619355 | 0.71 | ITGB3 (0.39) | CYP19A1MEN1KMT2A | |
| SCHEMBL8618280 | 0.68 | ITGB3 (0.34) | CYP19A1MEN1KMT2A | |
| SCHEMBL28881106 | 0.67 | CASP3 (0.34) | KMT2A | |
| SCHEMBL27796315 | 0.66 | ACE (0.35) | — | |
| SCHEMBL8617256 | 0.65 | ITGB3 (0.42) | CYP19A1 | |
| SCHEMBL10530028 | 0.65 | CYP19A1 (1.00) | CYP19A1CYP17A1 | |
| SCHEMBL10528175 | 0.64 | CYP19A1 (0.87) | CYP19A1CYP17A1 | |
| SCHEMBL15016185 | 0.64 | NOS3 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852045-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-22 | — | — | US | disclosed |