Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | NAT1 | P18440 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619012 | 0.91 | PTGS2 (0.60) | PTGS2PTGS1NAT1PIM1CTRC | |
| SCHEMBL8619011 | 0.83 | PTGS2 (0.44) | PTGS2PTGS1MEN1ALDH1A1GAA | |
| SCHEMBL8620558 | 0.81 | CRHBP (0.60) | NAT1MEN1NPC1POLBKMT2A | |
| SCHEMBL8309757 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1NAT1MEN1NPC1 | |
| SCHEMBL7768284 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1NAT1MEN1NPC1 | |
| SCHEMBL8618544 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1NAT1MEN1NPC1 | |
| SCHEMBL8536869 | 0.76 | PTGS2 (0.76) | PTGS2PTGS1NAT1MEN1NPC1 | |
| SCHEMBL8536872 | 0.76 | PTGS2 (0.76) | PTGS2PTGS1NAT1MEN1NPC1 | |
| SCHEMBL8614425 | 0.74 | PIM1 (0.53) | NAT1NPC1GAAPIM1PIM3 | |
| SCHEMBL8640744 | 0.74 | HPGD (0.47) | MEN1NPC1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767121-A | ANTIINFLAMMATORY AND -ARTHRITIC AGENTS; ANTIPYRETICS; ANALGESICS; ADHESION PROTEIN EXPRESSION AND CYCLOXYGENASE AND 5-LIPOXYGENASE INHIBITORS; IMMUNOSUPPRESSANTS AND -MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-16 | — | — | US | disclosed |