Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | TACR3 | P29371 | 2/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521896 | 0.78 | TACR3 (0.43) | HPGDTACR3SLC6A9SLC6A5MAPT | |
| SCHEMBL9330012 | 0.76 | ALDH1A1 (0.47) | HPGDTACR3ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11814585 | 0.70 | FOLH1 (0.41) | TACR3HSD17B2 | |
| SCHEMBL8082564 | 0.69 | MEN1 (0.49) | HPGDMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9795277 | 0.68 | HPGDS (0.49) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL10667146 | 0.68 | MTNR1A (0.44) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7398090 | 0.68 | LMNA (0.50) | ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL11700544 | 0.68 | MTNR1A (0.44) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8314839 | 0.68 | POLB (0.70) | TSHR | |
| SCHEMBL5992310 | 0.68 | KMT2A (0.53) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503597-B1 | Penam derivatives and processes for producing the same | OTSUKA KAGAKU KK (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5599925-A | BACTERICIDES | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5300497-A | Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5185330-A | Penicillins/ad/ | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| EP-0503597-A2 | Penam derivatives and processes for producing the same | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0164113-A2 | 3-pyrazolo(1,5-a)pyridinium cephem compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| EP-0164122-A2 | Cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |