Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CD74 | P04233 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624806 | 0.80 | HSD17B10 (0.35) | ALDH1A1PKML3MBTL1HPGDLMNA | |
| SCHEMBL8628216 | 0.77 | PDE10A (0.35) | ALDH1A1PKML3MBTL1HPGDLMNA | |
| SCHEMBL8918497 | 0.77 | DRD4 (0.53) | ALDH1A1LMNA | |
| SCHEMBL8918424 | 0.76 | HTR1A (0.51) | SIGMAR1 | |
| SCHEMBL7326070 | 0.76 | ALDH1A1 (0.35) | ALDH1A1PKML3MBTL1HPGDLMNA | |
| SCHEMBL8626022 | 0.75 | ALDH1A1 (0.63) | SIGMAR1ALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL8625594 | 0.75 | PDE10A (0.32) | PDE10A | |
| SCHEMBL8630456 | 0.75 | PDE10A (0.36) | ALDH1A1PKML3MBTL1HPGDLMNA | |
| SCHEMBL8919081 | 0.73 | PDE1B (0.41) | ALDH1A1HPGDTSHR | |
| SCHEMBL8921700 | 0.73 | ALDH1A1 (0.42) | ALDH1A1PKMHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767128-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1998-06-16 | — | — | US | disclosed |
| US-5618819-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1997-04-08 | — | — | US | disclosed |
| EP-0691339-A1 | Amine derivatives of 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-ones and oxazolo(4,5-b)pyridin-2(3H)-ones, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |