Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630991 | 0.92 | LTA4H (0.34) | — | |
| SCHEMBL8630919 | 0.88 | HTR2A (0.30) | — | |
| SCHEMBL10599695 | 0.77 | KDM1A (0.32) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL10337805 | 0.74 | OPRM1 (0.30) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL8632114 | 0.74 | KDM1A (0.38) | — | |
| SCHEMBL8517224 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL8634390 | 0.73 | KDM1A (0.35) | — | |
| SCHEMBL8630877 | 0.72 | SLC10A2 (0.34) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL8634659 | 0.71 | MMP2 (0.33) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL8631964 | 0.70 | MMP2 (0.35) | OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449015-B1 | Difluoromethyl compounds and liquid criystal medium | MERCK PATENT GMBH (DE) | 1998-07-01 | — | — | EP | disclosed |
| EP-0449015-A2 | Difluoromethyl compounds and liquid criystal medium | MERCK PATENT GmbH (DE) | 1991-10-02 | — | — | EP | disclosed |