Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557110 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL8604248 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL8555600 | 0.76 | SIRT2 (0.43) | ALDH1A1TSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL8603252 | 0.75 | ALDH1A1 (0.41) | ALDH1A1MAPK1LMNASMN1; SMN2NPC1 | |
| SCHEMBL7471326 | 0.74 | MEN1 (0.39) | ALDH1A1TSHRMAPK1LMNAMEN1 | |
| SCHEMBL8551402 | 0.72 | MEN1 (0.39) | ALDH1A1TSHRMAPK1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL8602861 | 0.72 | MEN1 (0.39) | ALDH1A1MAPK1LMNASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL8632521 | 0.71 | LMNA (0.38) | ALDH1A1TSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL8554026 | 0.69 | KCNH2 (0.41) | ALDH1A1MAPK1LMNARAB9AMEN1 | |
| SCHEMBL8628591 | 0.68 | LOXL2 (0.41) | ALDH1A1TSHRMAPK1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |