Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908278 | 0.91 | ALDH1A1 (0.38) | TDP1ALDH1A1TSHRHSD11B1CA2 | |
| Sulfuric Acid SCHEMBL8628602 | 0.91 | ALDH1A1 (0.38) | TDP1ALDH1A1TSHRHSD11B1CA2 | |
| Trifluoromethanesulfonic Acid SCHEMBL29851847 | 0.86 | HSD11B1 (0.43) | TDP1ALDH1A1TSHRHSD11B1 | |
| Trifluoromethanesulfonic Acid SCHEMBL59634 | 0.86 | HSD11B1 (0.43) | TDP1ALDH1A1TSHRHSD11B1 | |
| SCHEMBL2634677 | 0.84 | HSD11B1 (0.36) | TDP1ALDH1A1TSHRHSD11B1RBP4 | |
| SCHEMBL9617862 | 0.84 | HSD11B1 (0.36) | TDP1ALDH1A1TSHRHSD11B1CA2 | |
| SCHEMBL31582661 | 0.84 | HSD11B1 (0.36) | TDP1ALDH1A1TSHRHSD11B1RBP4 | |
| SCHEMBL216497 | 0.84 | ALDH1A1 (0.48) | TDP1ALDH1A1TSHRCA2RBP4 | |
| SCHEMBL29851795 | 0.84 | ALDH1A1 (0.48) | TDP1ALDH1A1TSHRCA2RBP4 | |
| Phenolsulfonic Acid SCHEMBL5699278 | 0.84 | ENPP2 (0.42) | TDP1ALDH1A1TSHRHSD11B1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848288-A1 | Resist materials | LUCENT TECHNOLOGIES INC. (US) | 1998-06-17 | — | — | EP | disclosed |