SCHEMBL8628902

SCHEMBL8628902

CC(C)Oc1nc(Cl)nc(-c2ccccc2NC(=O)O)n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
ATM Q13315 1/20 0.38
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
ALDH1A1 P00352 6/20 0.36
KDM4E B2RXH2 4/20 0.36
TSHR P16473 2/20 0.36
NPSR1 Q6W5P4 3/20 0.36
LMNA P02545 2/20 0.36
PLA2G1B P04054 1/20 0.36
THRB P10828 1/20 0.36
NPY1R P25929 1/20 0.36
NPY2R P49146 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
HTT P42858 2/20 0.35
USP2 O75604 1/20 0.35
POLB P06746 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8632527 0.86 ALDH1A1 (0.43) MAPTL3MBTL1KMT2AMEN1ALDH1A1
SCHEMBL8629929 0.77 HSD17B10 (0.46) MAPTL3MBTL1KMT2AMEN1ALDH1A1
SCHEMBL8626823 0.77 MAPT (0.64) MAPTL3MBTL1ATMKMT2AMEN1
SCHEMBL8651447 0.76 GPR35 (0.42) MAPTL3MBTL1KMT2AMEN1ALDH1A1
SCHEMBL8631751 0.73 ALDH1A1 (0.47) MAPTL3MBTL1ATMKMT2AMEN1
SCHEMBL8630118 0.73 PIK3CD (0.41) MAPTL3MBTL1KMT2AMEN1ALDH1A1
SCHEMBL8630090 0.72 NTRK1 (0.46) MAPTL3MBTL1KMT2AMEN1ALDH1A1
SCHEMBL8628783 0.71 RAB9A (0.49) MAPTL3MBTL1ATMKMT2AMEN1
SCHEMBL8629851 0.71 KMT2A (0.60) MAPTL3MBTL1ATMKMT2AMEN1
SCHEMBL8627862 0.71 ALDH1A1 (0.46) MAPTL3MBTL1KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5847126-A N-azinyl-N'-(het) arylsulphonyl-ureas BAYER AKTIENGESELLSCHAFT (DE) 1998-12-08 US disclosed
US-5696257-A INTERMEDIATES FOR HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-09 US disclosed
US-5580842-A HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-12-03 US disclosed
US-5476936-A Herbicides BAYER AKTIENGESELLSCHAFT (DE) 1995-12-19 US disclosed