Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28507838 | 1.00 | LMNA (0.64) | LMNAGAAMAOBMAOAPOLB | |
| SCHEMBL1793658 | 0.84 | LMNA (0.63) | LMNAGAAMAOBMAOAPOLB | |
| SCHEMBL12397421 | 0.84 | LMNA (0.68) | LMNAGAAMAOBMAOAPOLB | |
| SCHEMBL1793660 | 0.84 | LMNA (0.63) | LMNAGAAMAOBMAOAPOLB | |
| SCHEMBL31513736 | 0.83 | GAA (0.58) | LMNAGAAMAOBMAOAPOLB | |
| SCHEMBL31513735 | 0.83 | GAA (0.58) | LMNAGAAMAOBMAOAPOLB | |
| SCHEMBL22306971 | 0.81 | LMNA (0.63) | LMNAGAAMAOBMAOAPOLB | |
| SCHEMBL81547 | 0.78 | LMNA (1.00) | LMNAGAAMAOBMAOAPOLB | |
| SCHEMBL18837889 | 0.78 | GAA (0.52) | LMNAGAAMAOBMAOAPOLB | |
| SCHEMBL18837890 | 0.78 | GAA (0.52) | LMNAGAAMAOBMAOAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110305091-B | Preparation method of Barosavir intermediate compound | 江苏理工学院 | 2021-05-18 | — | — | CN | claimed |
| US-10442769-B2 | Process for the preparation of intermediate of dolutegravir | HETERO RESEARCH FOUNDATION (IN) | 2019-10-15 | — | — | US | claimed |
| EP-3016935-B1 | PROCESS FOR THE PREPARATION OF INTERMEDIATE OF DOLUTEGRAVIR | HETERO RESEARCH FOUNDATION (IN) | 2018-09-05 | — | — | EP | claimed |
| US-20180148412-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATE OF DOLUTEGRAVIR | HETERO RESEARCH FOUNDATION (IN) | 2018-05-31 | — | — | US | claimed |
| US-9963430-B2 | Process for the preparation of intermediate of dolutegravir | HETERO RESEARCH FOUNDATION (IN) | 2018-05-08 | — | — | US | claimed |
| US-20170334858-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATE OF DOLUTEGRAVIR | HETERO RESEARCH FOUNDATION (IN) | 2017-11-23 | — | — | US | claimed |
| EP-3016935-A2 | PROCESS FOR THE PREPARATION OF INTERMEDIATE OF DOLUTEGRAVIR | Hetero Research Foundation (IN) | 2016-05-11 | — | — | EP | claimed |
| WO-2015001572-A2 | PROCESS FOR THE PREPARATION OF INTERMEDIATE OF DOLUTEGRAVIR | HETERO RESEARCH FOUNDATION (IN) | 2015-01-08 | — | — | WO | claimed |
| CN-119977929-A | Pyrone compound and preparation method and application thereof | 广东东阳光药业股份有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-112920202-B | Cap-dependent protease inhibitor | 北京凯因科技股份有限公司 | 2024-08-09 | — | — | CN | disclosed |
| US-12037333-B2 | Pyridopyrazine and pyridotriazine inhibitors of influenza virus replication | COCRYSTAL PHARMA, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-12037333-B2 | Pyridopyrazine and pyridotriazine inhibitors of influenza virus replication | COCRYSTAL PHARMA, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-12037333-B2 | Pyridopyrazine and pyridotriazine inhibitors of influenza virus replication | COCRYSTAL PHARMA, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| CN-113286793-B | Inhibitors of influenza virus replication of pyrrolopyrazines and pyridotriazines | 共结晶制药公司 | 2024-04-05 | — | — | CN | disclosed |
| US-20090286987-A1 | METALLOPROTEIN INHIBITORS | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO UCSD TECHNOLOGY TRANSFER OFFICE (US) | 2009-11-19 | — | — | US | disclosed |
| US-7579486-B2 | Metalloprotein inhibitors | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO (US) | 2009-08-25 | — | — | US | disclosed |
| US-7579486-B2 | Metalloprotein inhibitors | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO (US) | 2009-08-25 | — | — | US | disclosed |
| US-20070117848-A1 | METALLOPROTEIN INHIBITORS | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO | 2007-05-24 | — | — | US | disclosed |
| US-20070117848-A1 | METALLOPROTEIN INHIBITORS | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO | 2007-05-24 | — | — | US | disclosed |
| WO-2007002109-A2 | MULTIDENTATE PYRONE-DERIVED CHELATORS FOR MEDICINAL IMAGING AND CHELATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286987-A1 | METALLOPROTEIN INHIBITORS | SOD1, ZFX, SOD3 | LMNA 3336/4885GAA 156/4885MAOB 31/4885 |
| US-20170334858-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATE OF DOLUTEGRAVIR | CYP3A4, DHPS, MVD | LMNA 2182/4885GAA 505/4885MAOB 967/4885 |
| US-20180148412-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATE OF DOLUTEGRAVIR | CYP3A4, DHPS, MVD | LMNA 2182/4885GAA 505/4885MAOB 967/4885 |
| US-20070117848-A1 | METALLOPROTEIN INHIBITORS | SOD1, ZFX, SOD3 | LMNA 3336/4885GAA 156/4885MAOB 31/4885 |
| US-10442769-B2 | Process for the preparation of intermediate of dolutegravir | CYP3A4, DHPS, MVD | LMNA 2182/4885GAA 505/4885MAOB 967/4885 |
| US-12037333-B2 | Pyridopyrazine and pyridotriazine inhibitors of influenza virus replication | PLPBP, EIF2AK2, TYMP | LMNA 2998/4885GAA 3634/4885MAOB 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.