Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630170 | 0.93 | CDC7 (0.43) | PTGS2CDC7KDM4ERXFP1MAPT | |
| SCHEMBL8629982 | 0.92 | EDNRB (0.43) | PTGS2CDC7KDM4EMAPTPTGDR2 | |
| SCHEMBL8629928 | 0.91 | PTGS2 (0.43) | PTGS2CDC7KDM4EMAPTPTGDR2 | |
| SCHEMBL8632283 | 0.90 | PTGS2 (0.63) | PTGS2PTGS1MAPTMEN1POLB | |
| SCHEMBL8629118 | 0.88 | PTGS2 (0.57) | PTGS2PTGS1KDM4ERXFP1MAPT | |
| SCHEMBL8631438 | 0.88 | CYP1A2 (0.46) | PTGS2MAPTPTGDR2POLBKMT2A | |
| SCHEMBL8629382 | 0.88 | ALDH1A1 (0.41) | PTGS2CDC7PTGDR2MEN1POLB | |
| SCHEMBL8630525 | 0.86 | CCR4 (0.41) | PTGS2CDC7KDM4EMAPTPTGDR2 | |
| SCHEMBL8630859 | 0.85 | PTGS2 (0.44) | PTGS2PTGS1KDM4ERXFP1MAPT | |
| SCHEMBL8631550 | 0.85 | PTGS2 (0.58) | PTGS2PTGS1KDM4ERXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |