Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1192730 | 0.96 | ERN1 (0.53) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5012398 | 0.80 | ERN1 (0.59) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28324710 | 0.80 | ERN1 (0.55) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL129104 | 0.80 | ERN1 (0.59) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| Potassium Ion SCHEMBL3628026 | 0.79 | DNMT1 (0.44) | MAPTTDP1CA1CA2CA9 | |
| Ammonia Solution, Strong SCHEMBL8762521 | 0.79 | ERN1 (0.58) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3726105 | 0.79 | ERN1 (0.58) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| Potassium Ion SCHEMBL10726076 | 0.78 | CA1 (0.41) | ERN1TDP1CA1CA2CA9 | |
| Formaldehyde SCHEMBL10629971 | 0.77 | ERN1 (0.56) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| Potassium Ion SCHEMBL1819744 | 0.76 | CTRB1 (0.49) | ERN1MAPTNR4A1HTR6F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35795-E | PHOTOGRAPHIC FIXATIVES | FUJI HUNT PHOTOGRAPHIC CHEMICALS, INC. (US) | 1998-05-12 | — | — | US | claimed |
| EP-0583443-A4 | MAKING FLOWABLE ALKALI OR AMMONIUM THIOSULFATE OR SULFITE AND ITS PRODUCT-BY-PROCESS | FUJI HUNT PHOTO CHEM (BE) | 1994-07-27 | — | — | EP | disclosed |
| EP-0583443-A1 | MAKING FLOWABLE ALKALI OR AMMONIUM THIOSULFATE OR SULFITE AND ITS PRODUCT-BY-PROCESS | FUJI HUNT PHOTOGRAPHIC CHEMICALS, N.V. (BE) | 1994-02-23 | — | — | EP | disclosed |
| WO-1993015437-A1 | MAKING FLOWABLE ALKALI OR AMMONIUM THIOSULFATE OR SULFITE AND ITS PRODUCT-BY-PROCESS | FUJI HUNT PHOTOGRAPHIC CHEMICALS, INC. (US) | 1993-08-05 | — | — | WO | disclosed |
| US-4041193-A | APPLYING AN ADHESIVE CONTAINING A SODIUM OR POTASSIUM SALT OF NAPHTHALENESULFONATE-FORMALDEHYDE CONDENSATE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-09 | — | — | US | disclosed |