Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633035 | 0.86 | FDPS (0.33) | HTTFDPS | |
| SCHEMBL8635924 | 0.84 | SLC9A1 (0.43) | — | |
| SCHEMBL8634357 | 0.80 | TYK2 (0.34) | — | |
| SCHEMBL8630815 | 0.77 | ACP1 (0.40) | — | |
| SCHEMBL8631380 | 0.77 | HTT (0.34) | HTT | |
| SCHEMBL8634502 | 0.77 | PTGS1 (0.38) | — | |
| SCHEMBL8635911 | 0.76 | TYK2 (0.47) | — | |
| SCHEMBL8635140 | 0.74 | BCAT2 (0.42) | — | |
| SCHEMBL8635462 | 0.73 | PDE4B (0.41) | — | |
| SCHEMBL8635031 | 0.73 | SLC9A1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057999-C | 4-Aminobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 2000-11-01 | — | — | CN | disclosed |
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |
| CN-1138575-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 1996-12-25 | — | — | CN | disclosed |