Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.33 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.32 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630803 | 0.86 | HTT (0.32) | FDPSHTT | |
| SCHEMBL8635031 | 0.84 | SLC9A1 (0.56) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8634301 | 0.79 | SLC9A1 (0.36) | SLC9A1 | |
| SCHEMBL8632612 | 0.76 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL8636380 | 0.76 | HTT (0.33) | SLC9A1SLC9A3SLC9A2HTT | |
| SCHEMBL8635344 | 0.76 | KMT2A (0.36) | SLC9A1 | |
| SCHEMBL8634805 | 0.75 | TYK2 (0.48) | HTT | |
| SCHEMBL8635924 | 0.73 | SLC9A1 (0.43) | SLC9A1 | |
| SCHEMBL8635463 | 0.73 | AKR1C3 (0.45) | — | |
| SCHEMBL8635848 | 0.72 | CYP11B2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057999-C | 4-Aminobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 2000-11-01 | — | — | CN | disclosed |
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |
| CN-1138575-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 1996-12-25 | — | — | CN | disclosed |