Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628067 | 0.87 | SMN1; SMN2 (0.43) | POLBMAPTACLYMEN1KMT2A | |
| SCHEMBL8631045 | 0.86 | STAT3 (0.42) | ACLYKDM4ECCR4TSHRSMN1; SMN2 | |
| SCHEMBL8631080 | 0.84 | KMO (0.52) | ACLYKDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL8628949 | 0.81 | ALDH1A1 (0.43) | POLBMAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL8632286 | 0.81 | KIT (0.45) | MAPTKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL8758715 | 0.81 | ALDH1A1 (0.43) | POLBMAPTACLYKDM4EMEN1 | |
| SCHEMBL8632208 | 0.81 | STAT3 (0.51) | POLBMAPTKMT2ASMN1; SMN2PRKAB2 | |
| SCHEMBL8627973 | 0.80 | KDM1A (0.51) | POLBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL8631659 | 0.80 | NAT1 (0.53) | MAPTACLYKDM4ENPSR1RXFP1 | |
| SCHEMBL8656731 | 0.79 | MCOLN3 (0.53) | POLBMAPTACLYKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |