Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8758715 | 0.93 | ALDH1A1 (0.43) | SMN1; SMN2POLBMAPTLMNAAAK1 | |
| SCHEMBL8631045 | 0.87 | STAT3 (0.42) | SMN1; SMN2TSHRFFAR4CCR4LMNA | |
| SCHEMBL8631173 | 0.87 | POLB (0.43) | SMN1; SMN2TSHRPOLBMAPTCCR4 | |
| SCHEMBL8627771 | 0.86 | ALDH1A1 (0.47) | SMN1; SMN2TSHRPOLBMAPTLMNA | |
| SCHEMBL8630028 | 0.85 | ALDH1A1 (0.45) | SMN1; SMN2TSHRFFAR4MAPTCYTH2 | |
| SCHEMBL8632286 | 0.82 | KIT (0.45) | MAPTCCR4LMNAKEAP1MEN1 | |
| SCHEMBL8632208 | 0.81 | STAT3 (0.51) | SMN1; SMN2FFAR4POLBMAPTLMNA | |
| SCHEMBL8632837 | 0.81 | LMNA (0.51) | FFAR4POLBMAPTLMNAKEAP1 | |
| SCHEMBL8631345 | 0.81 | MCL1 (0.49) | SMN1; SMN2TSHRFFAR4MAPTLMNA | |
| SCHEMBL8632810 | 0.80 | STAT3 (0.42) | TSHRFFAR4MAPTCYTH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |