Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 3/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.36 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631080 | 0.86 | KMO (0.52) | CCR2KMOKDM4ENPSR1RXFP1 | |
| SCHEMBL8628203 | 0.82 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KDM4ENPSR1GAA | |
| SCHEMBL8631173 | 0.81 | POLB (0.43) | ALDH1A1SMN1; SMN2KMOKDM4ENPSR1 | |
| SCHEMBL8627973 | 0.80 | KDM1A (0.51) | ALDH1A1KDM4ENPSR1RXFP1GAA | |
| SCHEMBL8630028 | 0.79 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL8631659 | 0.79 | NAT1 (0.53) | KDM4ENPSR1RXFP1MAPTPIK3CD | |
| SCHEMBL8632286 | 0.78 | KIT (0.45) | ALDH1A1KDM4ENPSR1RXFP1GAA | |
| SCHEMBL8632837 | 0.78 | LMNA (0.51) | ALDH1A1KDM4EGAAPOLBMAPT | |
| SCHEMBL8631345 | 0.77 | MCL1 (0.49) | ALDH1A1SMN1; SMN2KDM4EHPGDMAPT | |
| SCHEMBL8632810 | 0.76 | STAT3 (0.42) | ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |