Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936707 | 0.84 | LMNA (0.50) | PTGS2LMNAALDH1A1FLT1FLT4 | |
| SCHEMBL242381 | 0.83 | FLT1 (0.46) | PTGS2LMNAALDH1A1FLT1FLT4 | |
| SCHEMBL31531993 | 0.83 | FLT1 (0.50) | PTGS2LMNAALDH1A1FLT1FLT4 | |
| SCHEMBL12638410 | 0.83 | PTGS2 (0.58) | PTGS2LMNAALDH1A1PTGS1MAPT | |
| SCHEMBL3386873 | 0.83 | FLT1 (0.50) | PTGS2LMNAALDH1A1FLT1FLT4 | |
| SCHEMBL755309 | 0.82 | LMNA (0.60) | PTGS2LMNAALDH1A1PTGS1MAPT | |
| SCHEMBL13277970 | 0.81 | FLT1 (0.49) | PTGS2LMNAALDH1A1FLT1FLT4 | |
| Hydrochloric Acid SCHEMBL3866369 | 0.81 | FLT1 (0.49) | PTGS2LMNAALDH1A1FLT1FLT4 | |
| SCHEMBL8887426 | 0.81 | LMNA (0.67) | PTGS2LMNAALDH1A1FLT1FLT4 | |
| SCHEMBL8887429 | 0.81 | FLT1 (0.49) | PTGS2LMNAALDH1A1FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886723-A | Synthesis method of 2-chloro-4-methylsulfonyl benzoic acid | 辽宁龙田化工科技有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117263832-A | Synthesis method of 2-chloro-4-methylsulfonyl benzoic acid | 辽宁龙田化工科技有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-113735745-B | Preparation method of 2-chloro-4-methylsulfonyl benzoic acid | 武汉强丰新特科技有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-113896665-B | Preparation method of 2-chloro-1-methyl-4- (methylsulfonyl) benzene | 湖北工程学院 | 2023-04-07 | — | — | CN | claimed |
| CN-113896665-A | Preparation method of 2-chloro-1-methyl-4- (methylsulfonyl) benzene | 湖北工程学院 | 2022-01-07 | — | — | CN | claimed |
| CN-113735745-A | Preparation method of 2-chloro-4-methylsulfonylbenzoic acid | 武汉强丰新特科技有限公司 | 2021-12-03 | — | — | CN | claimed |
| CN-113603626-A | Preparation method of free radical initiator and application of free radical initiator in oxidation reaction | 武汉强丰新特科技有限公司 | 2021-11-05 | — | — | CN | claimed |
| CN-207348145-U | A kind of Emergency water supply device for the chloro- 4- methylsulfonyltoluenes reaction kettles of 2- | 倍合德华强(连云港)医药化工科技有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-104086466-B | The preparation method of the thiamphenicol benzoic acid of 2 chlorine 4 | 倍合德华强(连云港)医药化工科技有限公司 | 2017-11-21 | — | — | CN | claimed |
| CN-105017101-B | Synthesizing method of 2-chloro-4-(methylsulfonyl)benzoic acid | 浙江大学 | 2017-03-22 | — | — | CN | claimed |
| CN-102627591-B | Preparation method of 2-chloro-4-methylsulfonylbenzoic acid | SUZHOU LUOSEN AUX IES CO LTD | 2013-11-06 | — | — | CN | claimed |
| CN-102126996-B | Preparation method of 2-chlorin-4-mesyl benzoic acid | SINOCHEM CORPORATION (CN) | 2013-10-23 | — | — | CN | claimed |
| CN-102627591-A | Preparation method of 2-chloro-4-methylsulfonylbenzoic acid | SUZHOU LUOSEN AUX IES CO LTD | 2012-08-08 | — | — | CN | claimed |
| CN-102126996-A | Preparation method of 2-chlorin-4-mesyl benzoic acid | SINOCHEN CORP | 2011-07-20 | — | — | CN | claimed |
| US-20100298392-A1 | Isoindoline Derivatives For The Treatment Of Arrhythmias | ASTRAZENECA AB (SE) | 2010-11-25 | — | — | US | claimed |
| EP-2049484-A1 | ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS | AstraZeneca AB (SE) | 2009-04-22 | — | — | EP | claimed |
| WO-2008008022-A1 | ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2008-01-17 | — | — | WO | claimed |
| US-20080015237-A1 | NEW COMPOUNDS I/418 | ASTRAZENECA AB (SE) | 2008-01-17 | — | — | US | claimed |
| EP-0571405-A1 | PROCESS FOR PREPARING 4-ALKYLSULFONYL-1-ALKYL-2-CHLOROBENZENES AND THE LIKE. | HOECHST AG (DE) | 1993-12-01 | — | — | EP | claimed |
| WO-1992014700-A1 | PROCESS FOR PREPARING 4-ALKYLSULFONYL-1-ALKYL-2-CHLOROBENZENES AND THE LIKE | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015237-A1 | NEW COMPOUNDS I/418 | KCNH1, KCNH2, KCNH3 | PTGS2 3155/4885LMNA 228/4885ALDH1A1 315/4885 |
| US-20100298392-A1 | Isoindoline Derivatives For The Treatment Of Arrhythmias | KCNH1, KCNH2, KCNQ2 | PTGS2 1379/4885LMNA 461/4885ALDH1A1 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.