SCHEMBL8631990

SCHEMBL8631990

FC(F)(F)c1cc(Oc2ccc3ccccc3c2)ccc1OCC=C(Cl)Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARG Q86W56 1/20 0.41
MAPK10 P53779 1/20 0.39
AR P10275 6/20 0.38
MAPT P10636 2/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
ABL1 P00519 1/20 0.35
GAA P10253 2/20 0.35
RCE1 Q9Y256 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
AGXT P21549 2/20 0.34
PTPN7 P35236 1/20 0.34
TDP1 Q9NUW8 2/20 0.34
NPC1 O15118 1/20 0.34
XBP1 P17861 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SUCNR1 Q9BXA5 1/20 0.34
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634174 0.90 AR (0.39) ARMAOBMRGPRX4
SCHEMBL8638227 0.88 PARG (0.39) PARGMAPK10ARMAPTLMNA
SCHEMBL8638861 0.88 AR (0.38) ARMAPTGAAMAOBSMN1; SMN2
SCHEMBL8636008 0.87 AR (0.38) AR
SCHEMBL8635779 0.86 AR (0.39) ARMAPTHTTGAAMAOB
SCHEMBL8636474 0.85 RXRA (0.38) ARMAPTLMNAMAOBRAB9A
SCHEMBL8632777 0.85 FFAR4 (0.40) ARMRGPRX4
SCHEMBL8633895 0.84 AR (0.51) MAPK10ARMAOBMRGPRX4
SCHEMBL8633081 0.84 MAOB (0.43) ARMAOBKDM4EMRGPRX4ALDH1A1
SCHEMBL8634961 0.84 RXRA (0.35) ARMAPTLMNAHTTMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed