Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633215 | 0.86 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1GAALMNATAS2R14 | |
| SCHEMBL27369277 | 0.85 | SCN1A (0.39) | L3MBTL1TSHRALDH1A1LMNAPOLB | |
| SCHEMBL7764007 | 0.84 | SLC9A1 (0.43) | — | |
| SCHEMBL8634536 | 0.84 | CXCL8 (0.43) | ALDH1A1GAALMNAKDM4EHPGD | |
| SCHEMBL8635172 | 0.83 | CXCL8 (0.42) | TSHRALDH1A1GAALMNAALOX15 | |
| SCHEMBL8635140 | 0.81 | BCAT2 (0.42) | L3MBTL1ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL8636186 | 0.81 | AKR1C3 (0.44) | L3MBTL1TSHRALDH1A1LMNAKDM4E | |
| SCHEMBL8635360 | 0.81 | TBXA2R (0.41) | ALDH1A1LMNAPOLB | |
| SCHEMBL8632351 | 0.81 | PDE4B (0.41) | ALDH1A1LMNAPDK1PDK2PDK3 | |
| SCHEMBL8633397 | 0.80 | AKR1C3 (0.43) | TSHRALDH1A1GAALMNATAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |