Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632351 | 0.88 | PDE4B (0.41) | TBXA2RMCL1LMNACYP11B1CYP11B2 | |
| SCHEMBL8636256 | 0.86 | TBXA2R (0.44) | TBXA2RMCL1MERTKALDH1A1 | |
| SCHEMBL8633969 | 0.86 | CNR2 (0.43) | LMNAPOLB | |
| SCHEMBL8635300 | 0.85 | HTT (0.38) | TBXA2RALDH1A1 | |
| SCHEMBL8635140 | 0.84 | BCAT2 (0.42) | POLBALDH1A1 | |
| SCHEMBL27368430 | 0.84 | VNN1 (0.42) | — | |
| SCHEMBL7764854 | 0.84 | SLC9A1 (0.44) | — | |
| SCHEMBL8634230 | 0.83 | AKR1C3 (0.45) | LMNAPOLBALDH1A1 | |
| SCHEMBL8634502 | 0.82 | PTGS1 (0.38) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7764117 | 0.82 | AKR1C3 (0.42) | MCL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |