Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381714 | 0.77 | LMNA (0.39) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL8380440 | 0.76 | PTGER3 (0.56) | ATMLMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL8382692 | 0.75 | HTR1A (0.35) | HTR1AADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL8379003 | 0.75 | ALDH1A1 (0.36) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL8381832 | 0.75 | ALDH1A1 (0.36) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL3235018 | 0.75 | ALDH1A1 (0.62) | L3MBTL1LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL8435541 | 0.74 | RARG (0.37) | HTR1AADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL9364775 | 0.74 | FDPS (0.39) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL9364780 | 0.74 | FDPS (0.39) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL10477126 | 0.74 | KDM4E (0.60) | ATMLMNAMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712266-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-01-27 | — | — | US | disclosed |