SCHEMBL8634075

SCHEMBL8634075

CCCC(N1CCN(c2ccncc2)CC1)S(=O)(=O)N(Cc1ccccc1)C(C)=O

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RORC P51449 19/20 0.45
RORB Q92753 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633897 0.79 HRH3 (0.35)
SCHEMBL8636258 0.77 OPRM1 (0.36) RORC
SCHEMBL8636978 0.72 ITGB3 (0.41) RORC
SCHEMBL8636543 0.69 ITGB3 (0.41) RORCRORB
Hydrochloric Acid SCHEMBL8837964 0.69 ITGB3 (0.45)
SCHEMBL8636968 0.67 DRD4 (0.45) RORCRORB
SCHEMBL8637900 0.66 OPRD1 (0.42)
SCHEMBL8636260 0.66 SPHK1 (0.35) RORC
SCHEMBL22751990 0.65 CHKA (0.47)
SCHEMBL8637905 0.65 ITGB3 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5753659-A ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, ZENECA LIMITED (GB) 1998-05-19 US disclosed