Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 6/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636978 | 0.72 | ITGB3 (0.41) | RORC | |
| SCHEMBL8634088 | 0.71 | ITGB3 (0.36) | RORC | |
| SCHEMBL8635262 | 0.68 | ITGB3 (0.48) | — | |
| SCHEMBL8632400 | 0.67 | MEN1 (0.39) | RORCHTR1ADRD2 | |
| SCHEMBL8634075 | 0.67 | RORC (0.45) | RORCRORB | |
| SCHEMBL7493712 | 0.66 | DRD4 (0.61) | DRD4SLC6A4HTR2AHTR1ADRD2 | |
| SCHEMBL8632726 | 0.65 | KHK (0.44) | DRD4RORC | |
| SCHEMBL7403454 | 0.65 | DRD4 (0.59) | DRD4SLC6A4HTR1ADRD2 | |
| SCHEMBL12261943 | 0.64 | DRD4 (0.77) | DRD4HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL8699932 | 0.63 | GAA (0.42) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |